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Centre for Commercialization of Regenerative Medicine - CCRM

$15 million for 2011-17
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Centre for Commercialization of Regenerative Medicine

Number of partners

Partner contributions
$16 million

Toronto, Ontario

President and CEO
Michael May Michael May

Chief Scientific Officer
Peter Zandstra Peter Zandstra

Board chair
Gregory Bonfiglio Gregory Bonfiglio
Founder and Managing Partner, Proteus Venture Partners

Turning the promise of regenerative medicine into reality

The opportunity

Regenerative medicine (RM)-based therapies hold enormous potential to repair, regenerate or replace diseased cells, tissues and organs. But many of these potentially life-changing treatments never reach patients because they are not successfully moved from the lab to the clinic. Fortunately, Canada is a global hotbed for stem cell research, bioengineering and biomaterials. Building on this expertise, stem cell scientists and bioengineers across six RM centres in Ontario supported the creation of a new commercialization centre that would bridge the gap between academia and industry and enable promising technologies to reach the market.

How CCRM is seizing the opportunity

The Centre for Commercialization of Regenerative Medicine (CCRM) overcomes two major bottlenecks in RM commercialization: a dearth of early stage capital and access to centralized research infrastructure. CCRM provides small- and medium-sized enterprises, large multinationals and emerging biotechnology companies with a single entry point for accessing Canada-wide RM expertise and infrastructure. CCRM’s industry consortium of nearly 50 Canadian and international RM companies can also access a fully resourced, 550 square metre development facility designed for bioprocess optimization. CCRM is capitalizing on its extensive pipeline of ideas to bundle promising technologies into 10 new companies that are strategic and leverage expertise, funding and excellent science.

Among the results

  • CCRM’s partnership with the CellCAN Regenerative Medicine and Cell Therapy Network is harmonizing the operations of an 1,850 square metre state-of-the-art good manufacturing practice (GMP) cell manufacturing facility that is being built to support academic and private sector partners, and other existing facilities across Canada. The facility will be housed at CCRM and operated on behalf of the University Health Network.
  • Thanks to investments from CCRM, two Canadian companies launched in 2016: AVROBIO, a clinical-stage biotechnology company accelerating the development of two novel cell and gene therapies for patients with acute myeloid leukemia and Fabry disease, and Actium (now KisoJi Biotechnology Inc.), a cancer stem cell company whose platform has the potential to identify novel cancer stem cell molecular targets.
  • With funding from GE Healthcare and the Federal Economic Development Agency for Southern Ontario, CCRM is building a new centre for advanced therapeutic cell technologies in Toronto. The centre will provide cell therapy companies with facilities and expertise to establish manufacturing processes to produce the large cell numbers required for clinical and commercial use.
  • ExCellThera, a spin-off company launched by CCRM and the Institute for Research in Immunology and Cancer - Commercialization of Research, in partnership with Hopital Maisonneuve-Rosement, began its first clinical trial in 2016. The product represents a new therapeutic option for patients who require stem cell transplantation to treat acute myeloid leukemia and other malignant blood disorders, and who lack a traditional donor.

Connect with CCRM


June 23, 2016
December 23, 2014
December 11, 2014
October 20, 2014
January 2, 2014
Building Canada's Strengths: Regenerative Medicine
April 17, 2014
Canada is recognized as a global leader in stem cell and bioengineering science, with over 400 stem cell scientists working in 68 research centres within, or affiliated with, 25 Canadian universities. Given its rich history of research excellence in the field, this country is uniquely placed to be one of the earliest beneficiaries of stem cell advances. Read more
Building Canada's Strengths: Drug Discovery and Commercialization
April 17, 2014
Developing new drugs is a long, complex and expensive process. The NCE supports several models that are helping reduce the risk and accelerate the commercialization of medical innovations that will improve health-care delivery and patient care in Canada and abroad. Read more
Take it from the top – strong leadership means better results
November 14, 2012
The Board of Directors for an NCE network or centre often reads like the Who’s Who list of a particular sector, featuring top experts and prominent figures from industry and academia. Pulling together that room full of heavy hitters is an important part of the innovative approaches to governance and best practices adopted by NCE-funded organizations to achieve their goals. Read more
Watch Video
CCRM Sits Down With... Molly Shoichet, University of Toronto
May 1, 2014
Watch Video
Cell Culture with Bioreactors
March 31, 2014
Watch Video
CCRM Sits down with... Michael D. West, CEO of BioTime
November 29, 2013
Watch Video
CCRM Sits Down with... Stephen Minger
November 4, 2013